Microfluidic device iLiNP1.0, 2.0
・This model consists of a microfluidic chip and tubing connection components (accessories).
・By combining with a commercially available pump, an experimental environment for nanoparticle formulation can be easily constructed.
Microfluidic chips (as of July 2024)
Configurations
Example 1
Syringe pumps and microfluidic chip connected by 0.5mm OD capillary tubings.
1. Microfluidic chip (COP-iLiNP1.0S, COP-iLiNP1.0SW or QUA-iLiNP2.0S)
2. Chip holder S (ACC-CHO02S)
3. Holder connector and ferrule for 0.5mm OD capillary tube (ACC-HCF01)
4. 0.5mm OD PEEK capillary tube (ACC-PEK01)
5. Syringe connector and ferrule for 0.5mm OD capillary tube (ACC-SCF01)
6. Luer lock syringes
7. Syringe pumps
Example 2
Syringe pumps and microfluidic chip connected by 1/16” OD capillary tubings.
1. Microfluidic chip (COP-iLiNP1.0S, COP-iLiNP1.0SW or QUA-iLiNP2.0S)
2. Chip holder S (ACC-CHO02S)
3. Holder connector and ferrule for 1/16” OD tube (ACC-HCF02)
4. 1/16” OD PTFE tube (ACC-TEF01)
5. Connector (ACC-CON02)
6. Union (ACC-U1602)
7. Female luer lock connector (ACC-LUR01)
8. Luer lock syringes
9. Syringe pumps
Example 3
Plunger pumps and microfluidic chip connected by 1/16” OD capillary tubings.
1. Microfluidic chip (COP-iLiNP1.0S, COP-iLiNP1.0SW or QUA-iLiNP2.0S)
2. Chip holder S (ACC-CHO02S)
3. Holder connector and ferrule for 1/16” OD tube (ACC-HCF02)
4. 1/16” OD PTFE tube (ACC-TEF01)
5. Connector
6. Plunger pumps
LiNAS-M, LiNAS-mini
・This model can be used with low-cost PDMS microfluidic chips.
・The lineup includes two types: mini, which is used by connecting a commercially available pump, and LiNAS-M platform, which is equipped with two dedicated syringe pumps.
Microfluidic chips for LiNAS-M and LiNAS-mini (LM series)
Assembly of the microfluidic device
If the microfluidic chip is damaged, only the chip can be replaced.
LiNAS-M (model LM-003)
・Multifunctional model equipped with two syringe pumps that allow free flow rate setting.
・Anyone can easily and reproducibly manufacture lipid nanoparticles and polymer nanoparticles of various sizes.
Features #1
Easy installation of the microfluidic device to the device by simply lifting up the microfluidic device.
Features #2
Glass syringes and disposable syringes can be used separately depending on the purpose and application.
The use of the glass syringes is recommended if you want to try several pumping conditions using the same raw material solution or if you want to prepare a large quantity of nanoparticles by repeating pumping in combination with using reservoir.
The use of the disposable syringes is recommended if you want to prepare prototype samples using different types of raw material solutions or if want to avoid the hassle of syringe cleaning.
Features (others)
・Easy to operate even for beginners.
・High reproducibility of nanoparticle production is achieved by using a high-precision pump.
・High flexibility of piping allows customers to easily customize the pumping route.
・Unlimited use of the dedicated microfluidic chip.
・Easy to control particle size by using iLiNP type microfluidic chip (patented technology).
・Flexibility to change the shape of the flow channel.
LiNAS-mini
・Basic model. Pump sold separately.
Feature
・The unique mechanism allows easy connection of the dedicated microfluidic chip and the pump.
LiMAP series (Sales scheduled for 2024 or later.)
・For GMP grade mass production of nanoparticles.
・Made-to-order machine.
