Mass production system for RNA-loaded lipid nanoparticles using piling up microfluidic devices.
Applied Materials Today 31 (2023) 101754
https://doi.org/10.1016/j.apmt.2023.101754

The iLiNP microfluidic device invented at Hokkaido University has been used by many users in Japan and overseas, mainly for the preparation of nanoparticle formulations on a laboratory scale. The demand for microfluidic devices that enable mass production of nano-particle formulations is also increasing rapidly.
A research team from Hokkaido University and Shin-Etsu Chemical Co., Ltd. have developed a new microfluidic chip for the mass production of nanoparticle drugs. This research result is a significant achievement that will contribute to the expansion of capability in the development and production of nanoparticle formulations using Hokkaido University’s iLiNP technology.