Mass production system for RNA-loaded lipid nanoparticles using piling up microfluidic devices.
Applied Materials Today 31 (2023) 101754
The iLiNP microfluidic device invented at Hokkaido University has been used by many users in Japan and overseas, mainly for the preparation of nanoparticle formulations on a laboratory scale. The demand for microfluidic devices that enable mass production of nano-particle formulations is also increasing rapidly.
A research team from Hokkaido University and Shin-Etsu Chemical Co., Ltd. have developed a new microfluidic chip for the mass production of nanoparticle drugs. This research result is a significant achievement that will contribute to the expansion of capability in the development and production of nanoparticle formulations using Hokkaido University’s iLiNP technology.